SFB 914 Trafficking of Immune Cells in Inflammation, Development and Disease

Links and Functions

Breadcrumb Navigation


Prof. Dr. rer. nat. Hubert Hilbi


Project B07 (E)


Max von Pettenkofer-Institut

LMU München
Pettenkoferstr. 9a
80336 München

Phone: + 49 89 2180 72964
Fax: + 49 89 2180 72802

Five most relevant publications:

  1. Weber, S. S., Ragaz, C, Reus, K., Nyfeler Y., and Hilbi, H. (2006) Legionella pneumophila exploits PI(4)P to anchor secreted effector proteins to the replicative vacuole. PLoS Pathog. 2: e46.
  2. Spirig, T., Tiaden, A., Kiefer, P., Buchrieser, C., Vorholt, J. A., and Hilbi, H. (2008) The Legionella autoinducer synthase LqsA produces an α-hydroxyketone signaling molecule. J. Biol. Chem. 283: 18113-18123.
  3. Urwyler, S., Nyfeler, Y., Ragaz, C., Lee, H., Mueller, L. N., Aebersold, R., and Hilbi, H. (2009) Proteome analysis of Legionella vacuoles purified by magnetic immuno-separation reveals secretory and endosomal GTPases. Traffic 10: 76-87.
  4. Brombacher, E., Urwyler, S., Ragaz, C., Weber, S. S., Kami, K., Overduin, M., and Hilbi, H. (2009) Rab1 guanine nucleotide exchange factor SidM is a major PtdIns(4)P-binding effector protein of Legionella pneumophila. J. Biol. Chem. 284: 4846–4856.
  5. Weber, S. S., Ragaz, C., and Hilbi, H. (2009) The inositol polyphosphate-5-phosphatase OCRL1 restricts intracellular growth of Legionella, localizes to the replicative vacuole and binds to the bacterial effector LpnE. Cell Microbiol. 11: 442-460.